Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | PDE1A | P54750 | 2/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050884 | 0.86 | ATM (0.44) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21440776 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7984755 | 0.83 | LMNA (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL7989254 | 0.82 | CYP11B1 (0.49) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL5483136 | 0.80 | PKM (0.59) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28016892 | 0.79 | ALDH1A1 (0.47) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7987445 | 0.78 | PKM (0.57) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7984751 | 0.78 | NTRK1 (0.46) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7987920 | 0.78 | TP53 (0.47) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7987938 | 0.78 | KDM4E (0.44) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |