Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118386 | 0.81 | ALDH1A1 (0.41) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL4775813 | 0.80 | LOXL2 (0.42) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL2388976 | 0.73 | CNR2 (0.46) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL12507999 | 0.72 | TAS1R3 (0.41) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL586085 | 0.72 | GPR3 (0.44) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL2702753 | 0.72 | LOXL2 (0.63) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL719251 | 0.72 | GPR3 (0.44) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL1035524 | 0.72 | LOXL2 (0.48) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP | |
| SCHEMBL2845156 | 0.71 | TAS1R3 (0.44) | TAS1R3TAS1R1ALDH1A1PRNPRXFP1 | |
| SCHEMBL2387916 | 0.70 | CNR2 (0.49) | TAS1R3TAS1R1ALDH1A1LOXL2PRNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |