Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18382 | 0.84 | NR1H2 (0.41) | NUDT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2411422 | 0.80 | SMN1; SMN2 (0.43) | NUDT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL27859925 | 0.78 | LMNA (0.41) | NUDT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7270618 | 0.76 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL16551851 | 0.76 | LMNA (0.40) | LMNASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL28858783 | 0.76 | LMNA (0.42) | NUDT1LMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24725108 | 0.74 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2NPC1ALDH1A1TP53 | |
| SCHEMBL3543675 | 0.74 | ALKBH1 (0.44) | NUDT1SMN1; SMN2NPC1MAPT | |
| SCHEMBL27876512 | 0.74 | NPC1 (0.40) | LMNASMN1; SMN2NPC1TP53 | |
| SCHEMBL10586419 | 0.73 | NPC1 (0.35) | LMNASMN1; SMN2NPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262051-B1 | Fungicidal methoximinomethyldioxazines | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |