Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | STAT3 | P40763 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.35 |
| ▸ | SDHB | P21912 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984890 | 0.84 | NUDT1 (0.41) | NR1H2NR1H3NUDT1SMN1; SMN2LMNA | |
| SCHEMBL24725108 | 0.81 | SMN1; SMN2 (0.41) | PTGS2SMN1; SMN2LMNANPSR1TP53 | |
| SCHEMBL2411422 | 0.80 | SMN1; SMN2 (0.43) | NUDT1PTGS2SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL27859925 | 0.78 | LMNA (0.41) | NUDT1PTGS2SMN1; SMN2LMNANPSR1 | |
| SCHEMBL14857609 | 0.77 | LMNA (0.45) | PTGS2PTGS1SMN1; SMN2LMNACNR2 | |
| SCHEMBL7270618 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNANPSR1TP53HPGD | |
| SCHEMBL16551851 | 0.76 | LMNA (0.40) | PTGS2PTGS1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8637660 | 0.76 | LMNA (0.37) | NR1H2NR1H3PTGS2PTGS1SMN1; SMN2 | |
| SCHEMBL28858783 | 0.76 | LMNA (0.42) | NUDT1PTGS2PTGS1SMN1; SMN2LMNA | |
| SCHEMBL32665306 | 0.76 | LMNA (0.42) | SMN1; SMN2LMNANPSR1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895568-B2 | Compositions comprising substituted pteridines as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2013-09-26 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461164-B2 | Pteridines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2013-06-11 | — | — | US | disclosed |
| EP-2473511-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | Dow AgroSciences LLC (US) | 2012-07-11 | — | — | EP | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | MITSUBISHI PHAMA CORPORATION (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | MITSUBISHI PHAMA CORPORATION (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |
| EP-0749427-B1 | PYRIMIDINE FUNGICIDES | ZENECA LTD (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5723471-A | Pyrimidine fungicides | ZENECA LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| EP-0749427-A1 | PYRIMIDINE FUNGICIDES | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024396-A1 | PYRIMIDINE FUNGICIDES | ZENECA LIMITED (GB) | 1995-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167307-A1 | Carboxylic Acid Derivative Containing Thiazole Ring and Pharmaceutical Use Thereof | PPARA, PPARD, PPARG | NR1H2 22/4885NR1H3 29/4885NUDT1 2349/4885 |
| US-20130252960-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | CBR3, CBR1, AKR1C4 | NR1H2 859/4885NR1H3 1047/4885NUDT1 456/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | NR1H2 2346/4885NR1H3 2247/4885NUDT1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.