Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974069 | 0.94 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CXCR2KMT2AHPGD | |
| SCHEMBL7988015 | 0.90 | HPGD (0.43) | ALDH1A1SMN1; SMN2CXCR2KMT2AHPGD | |
| SCHEMBL7987948 | 0.89 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2CXCR2KMT2AHPGD | |
| SCHEMBL7987251 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDCYP1A2 | |
| SCHEMBL7975265 | 0.86 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KMT2AHPGDMEN1 | |
| SCHEMBL7974010 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2CXCR2KMT2AHPGD | |
| SCHEMBL7984655 | 0.85 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7987658 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDKDM4E | |
| SCHEMBL7985332 | 0.84 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2CXCR2KMT2AHPGD | |
| SCHEMBL7988590 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |