Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987818 | 0.90 | KMT2A (0.49) | KMT2APARP10MAPTNPSR1POLB | |
| SCHEMBL7990723 | 0.85 | KMT2A (0.58) | KMT2APARP10MAPTNPSR1POLB | |
| SCHEMBL7984823 | 0.84 | KAT6A (0.48) | KMT2AALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7983730 | 0.82 | CES2 (0.50) | PARP10MAPTPTGS2 | |
| SCHEMBL7985087 | 0.81 | PARP10 (0.54) | KMT2APARP10NPSR1ALDH1A1HPGD | |
| SCHEMBL7973511 | 0.79 | USP5 (0.45) | KMT2AMAPTPOLBALDH1A1HTT | |
| SCHEMBL7973512 | 0.78 | TSHR (0.54) | KMT2ATP53ALDH1A1HPGDRAB9A | |
| SCHEMBL7990725 | 0.76 | ALDH1A1 (0.45) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL7987131 | 0.75 | HTR7 (0.44) | KMT2APOLBPTGS2ALDH1A1HPGD | |
| SCHEMBL14879107 | 0.75 | KMT2A (0.61) | KMT2APARP10MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |