Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | CES2 | O00748 | 3/20 | 0.62 |
| ▸ | CES1 | P23141 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836826 | 0.81 | LMNA (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL15955701 | 0.81 | CES2 (0.60) | LMNACES2CES1MAPTTSHR | |
| SCHEMBL7007282 | 0.80 | LMNA (0.67) | LMNACES2CES1MAPTALDH1A1 | |
| SCHEMBL2528895 | 0.80 | LMNA (0.67) | LMNACES2CES1MAPTALDH1A1 | |
| SCHEMBL29116440 | 0.79 | LMNA (0.66) | LMNACES2CES1MAPTALDH1A1 | |
| SCHEMBL8027218 | 0.79 | CES2 (0.61) | LMNACES2CES1MAPTALDH1A1 | |
| Benzoin SCHEMBL2025536 | 0.78 | CES2 (1.00) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL901258 | 0.78 | CES2 (1.00) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL145 | 0.78 | CES2 (1.00) | LMNACES2CES1TSHRALDH1A1 | |
| Benzoin SCHEMBL5833429 | 0.78 | CES2 (1.00) | LMNACES2CES1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172093-B1 | PESTICIDES, INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5969147-A | Substituted biphenyloxazolines | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-19 | — | — | US | disclosed |
| EP-0696584-B1 | Substituted biphenyloxazolines and their use as fungicides | BAYER AG (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0696584-A1 | Substituted biphenyloxazolines and their use as fungicides | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |