Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738491 | 0.81 | FFAR1 (0.44) | ACACB | |
| SCHEMBL6426394 | 0.79 | PTGS2 (0.35) | ACACB | |
| SCHEMBL5735231 | 0.79 | ACACB (0.41) | ACACB | |
| SCHEMBL7985128 | 0.74 | ACE2 (0.34) | ACE2 | |
| SCHEMBL7980972 | 0.72 | SLC6A2 (0.33) | ACE2 | |
| SCHEMBL7984067 | 0.70 | RARB (0.36) | ACE2ACACB | |
| SCHEMBL10412862 | 0.69 | GABRP (0.41) | — | |
| SCHEMBL7987639 | 0.66 | HNF4A (0.37) | ACACB | |
| SCHEMBL27216854 | 0.65 | NEK2 (0.35) | — | |
| SCHEMBL7980771 | 0.65 | RARB (0.38) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303785-B1 | SUBSTITUTED N-CYCLOPROPYLTETRAHYDROISOQUINOLINES | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |