Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984296 | 0.83 | NFE2L2 (0.34) | MMP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7985333 | 0.78 | ALDH1A1 (0.38) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL7985329 | 0.75 | MMP1 (0.43) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL8071961 | 0.67 | MMP1 (0.35) | MMP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL7984321 | 0.64 | HTT (0.49) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL7984313 | 0.64 | HTT (0.49) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL28270090 | 0.62 | PKM (0.50) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL7210792 | 0.62 | MMP1 (0.43) | MMP1MMP2MMP9MMP13MMP3 | |
| SCHEMBL11562012 | 0.59 | F2 (0.54) | MMP1MMP2MMP9HTTNPSR1 | |
| SCHEMBL6382556 | 0.59 | HTT (0.43) | MMP1MMP2MMP9HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274758-B1 | ENANTIOMORPH SELECTIVITY | DARWIN DISCOVERY, LTD. (GB) | 2001-08-14 | — | — | US | disclosed |