Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991669 | 0.94 | HDAC1 (0.38) | HSD17B13CDK9BRD4EPHX2PPARG | |
| SCHEMBL7985791 | 0.91 | CYP11B1 (0.40) | HSD17B13CDK9BRD4EPHX2PPARG | |
| SCHEMBL7985299 | 0.90 | CDK9 (0.39) | HSD17B13CDK9BRD4EPHX2PPARG | |
| SCHEMBL7985613 | 0.90 | MET (0.46) | IDO1TDO2HSD17B13METCYP11B1 | |
| SCHEMBL7985360 | 0.89 | POLB (0.40) | HSD17B13CDK9HDAC1HDAC6 | |
| SCHEMBL7987253 | 0.89 | HPGDS (0.40) | METCYP11B1CYP11B2HDAC1HDAC6 | |
| SCHEMBL7988638 | 0.89 | MET (0.42) | IDO1HSD17B13CDK9BRD4EPHX2 | |
| SCHEMBL7985336 | 0.89 | PIK3CA (0.42) | HSD17B13CYP11B1CYP11B2HSD17B1HSD17B2 | |
| SCHEMBL7988958 | 0.87 | ALDH1A1 (0.42) | BRD4METCYP11B1CYP11B2 | |
| SCHEMBL7987310 | 0.87 | YTHDC1 (0.41) | HSD17B13CDK9HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |