Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890300 | 0.84 | MAPT (0.50) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL9522178 | 0.76 | MAPT (0.38) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL13461104 | 0.76 | CES2 (0.50) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL29193673 | 0.76 | KDM1A (0.35) | MAPTHSD17B10ALDH1A1CHRM2CHRM4 | |
| SCHEMBL679006 | 0.72 | CES1 (0.39) | MAPTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6664594 | 0.71 | HSD17B10 (0.59) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL950901 | 0.70 | SLC2A1 (0.37) | MAPTPOLBALDH1A1CHRM2CHRM4 | |
| SCHEMBL12352711 | 0.69 | SMN1; SMN2 (0.55) | MAPTALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL1279809 | 0.69 | BHMT (0.44) | MAPTBLMALDH1A1ALDH2CHRM2 | |
| SCHEMBL14331808 | 0.69 | LDHA (0.38) | MAPTBLMALDH1A1ALDH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | claimed |
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |