Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5726791 | 0.84 | NAAA (0.46) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7986084 | 0.78 | SMN1; SMN2 (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL5725348 | 0.75 | ALDH1A1 (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4ADRB1 | |
| SCHEMBL5862640 | 0.74 | MRGPRX4 (0.51) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5726264 | 0.73 | SLC2A1 (0.43) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5046669 | 0.73 | PTGES (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4ADRB1 | |
| SCHEMBL5725353 | 0.72 | MRGPRX4 (0.40) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5725361 | 0.72 | PLAAT3 (0.39) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5726132 | 0.72 | ALDH1A1 (0.46) | PLAAT3PLAAT5PLAAT2PLAAT4ADRB1 | |
| SCHEMBL5727377 | 0.72 | TAAR1 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |