Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987648 | 0.90 | HSP90AA1 (0.39) | LMNATDP1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7989824 | 0.90 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7989289 | 0.89 | CA1 (0.42) | ALDH1A1MEN1MAPK1KMT2AIDO1 | |
| SCHEMBL7989311 | 0.88 | CA1 (0.44) | HTTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7986279 | 0.88 | CA1 (0.45) | LMNAMAPTHTTALDH1A1MEN1 | |
| SCHEMBL7989863 | 0.87 | IDO1 (0.36) | LMNAALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL7987303 | 0.87 | HSP90AA1 (0.43) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7447822 | 0.86 | HSP90AA1 (0.44) | KDM4EMEN1MAPK1KMT2AIDO1 | |
| SCHEMBL7986289 | 0.84 | IDO1 (0.38) | LMNAMAPTHTTTDP1ALDH1A1 | |
| SCHEMBL7975758 | 0.84 | MAOB (0.48) | LMNAMAOBSCN9APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |