Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7223598 | 0.86 | OPRL1 (0.36) | CYP11B1CYP11B2CHRNB4CHRNA3 | |
| SCHEMBL6615383 | 0.84 | OPRM1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL7690570 | 0.84 | CYP11B2 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL6619579 | 0.81 | SLC6A4 (0.34) | — | |
| SCHEMBL7685774 | 0.79 | — | — | |
| SCHEMBL6617483 | 0.79 | CYP11B1 (0.30) | CYP11B1CYP11B2 | |
| SCHEMBL6615239 | 0.79 | — | — | |
| SCHEMBL6615641 | 0.78 | TRPA1 (0.30) | — | |
| SCHEMBL16554482 | 0.78 | CHRNB2 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL6618168 | 0.78 | CHRNB2 (0.32) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294545-B1 | INSECTICIDES | SYNGENTA LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1033914-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999026478-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |