Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ASPH | Q12797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL9668606 | 0.81 | MEN1 (0.40) | KMT2AMEN1KDM4EMAPTHTT | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL9084433 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EMAPTHTT | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL8588144 | 0.78 | MAPT (0.45) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL7986259 | 0.77 | MAPT (0.34) | KMT2AKDM4EMAPTGAALMNA | |
| SCHEMBL4031502 | 0.77 | GAA (0.44) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL9088391 | 0.75 | ADRA1A (0.41) | KMT2AMEN1KDM4EMAPTGAA | |
| SCHEMBL3743917 | 0.75 | ATM (0.32) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL8051642 | 0.72 | MAPT (0.45) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL3743974 | 0.72 | PARP1 (0.40) | KMT2AMEN1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262342-B1 | CHEMICALLY REGULATABLE DNA SEQUENCES DERIVED FROM 5' REGION OF GENES ENCODING PATHOGENESIS RELATED PROTEINS CAPABLE OF REGULATING TRANSCRIPTION OF AN ASSOCIATED DNA SEQUENCE IN PLANTS/TISSUES, CHIMERIC CONSTRUCTS, AND TRANSGENIC PLANTS | NOVARTIS FINANCE CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-5880328-A | ANTI-PATHOGENIC SEQUENCES DERIVED FROM NOVEL CDNAS CODING FOR PR PROTEINS WHICH CAN BE GENETICALLY ENGINEERED AND TRANSFORMED INTO PLANTS TO CONFER ENHANCED RESISTANCE TO DISEASE | NOVARTIS FINANCE CORPORATION (US) | 1999-03-09 | — | — | US | disclosed |
| US-5847258-A | DNA encoding β-1,3-glucanases | NOVARTIS FINANCE CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |