Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139518 | 0.99 | SIGMAR1 (0.52) | SIGMAR1SLC6A2SLC6A4SLC6A3LIPG | |
| SCHEMBL7986321 | 0.97 | SIGMAR1 (0.50) | SIGMAR1SLC6A2SLC6A4SLC6A3LIPG | |
| SCHEMBL8894163 | 0.92 | P2RX3 (0.50) | SIGMAR1LIPGP2RX3MAPK1STS | |
| SCHEMBL25045499 | 0.85 | OPRM1 (0.48) | SIGMAR1SLC6A3 | |
| SCHEMBL25043878 | 0.85 | HDAC1 (0.53) | SIGMAR1P2RX3 | |
| SCHEMBL1049753 | 0.84 | HDAC1 (0.50) | LIPGMAPK1STSACHE | |
| SCHEMBL8525648 | 0.82 | KMT2A (0.44) | MAPK1ACHE | |
| SCHEMBL7983866 | 0.81 | KMT2A (0.44) | MAPK1ACHE | |
| SCHEMBL4400064 | 0.81 | FAAH (0.49) | STS | |
| SCHEMBL7971782 | 0.81 | SIGMAR1 (0.69) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |