SCHEMBL7986608

SCHEMBL7986608

CCOC(=O)Cc1ccc2c(c1)OCO2

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.61
ALDH1A1 P00352 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
HSD17B10 Q99714 3/20 0.56
LMNA P02545 2/20 0.56
MEN1 O00255 1/20 0.56
USP2 O75604 1/20 0.56
MAPT P10636 1/20 0.56
ALOX15 P16050 1/20 0.56
KMT2A Q03164 1/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
HTT P42858 1/20 0.56
HPGD P15428 3/20 0.54
KLK7 P49862 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4140012 0.91 RAB9A (0.58) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL18392739 0.89 CYP3A4 (0.52) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL10881776 0.87 NPC1 (0.62) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL3186208 0.85 CYP3A4 (0.58) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL1744784 0.84 SMN1; SMN2 (0.64) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL11985734 0.84 CYP3A4 (0.57) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL11259822 0.83 CYP3A4 (0.56) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL29067230 0.83 CYP3A4 (0.64) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL12341995 0.81 CYP3A4 (0.53) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL14745413 0.81 CYP3A4 (0.53) CYP3A4ALDH1A1CYP1A2CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides DHANOA DALJIT SINGH (US) 2025-11-04 US disclosed
US-20240228491-A1 METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US disclosed
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT SINGH (US) 2023-02-09 US disclosed
WO-2021118826-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT (US) 2021-06-17 WO disclosed
WO-2021118826-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES DHANOA DALJIT (US) 2021-06-17 WO disclosed
US-6207686-B1 FOR THERAPY OF HYPERTENSION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-03-27 US disclosed
EP-0792265-A1 ENDOTHELIN ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-09-03 EP disclosed
WO-1996015109-A1 ENDOTHELIN ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-05-23 WO disclosed
US-4493823-A USING CARBOXYBENZENE COMPOUND HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1985-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039319-A1 DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES AGTR2, AGTR1, EDNRA CYP3A4 2346/4885ALDH1A1 2247/4885CYP1A2 1388/4885
US-12458624-B2 Deuterium-enriched substituted phenoxyphenyl acetic acids and acylsulfonamides AGTR2, AGTR1, EDNRA CYP3A4 2346/4885ALDH1A1 2247/4885CYP1A2 1388/4885
US-20240228491-A1 METHIONINE ADENOSYLTRANSFERASE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF MAT1A, AMD1, MAT2B CYP3A4 391/4885ALDH1A1 118/4885CYP1A2 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.