Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.33 |
| ▸ | Q9HBH1 | 2/20 | 0.33 | |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990047 | 0.83 | PDF (0.50) | ||
| SCHEMBL7990402 | 0.82 | PSEN1 (0.37) | ALDH1A1 | |
| SCHEMBL7990404 | 0.82 | PSEN1 (0.37) | ALDH1A1 | |
| SCHEMBL7993920 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7993921 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7986213 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7986250 | 0.77 | NOS3 (0.39) | ALDH1A1TSHREPHX2 | |
| SCHEMBL7986244 | 0.77 | NOS3 (0.39) | ALDH1A1TSHREPHX2 | |
| SCHEMBL7975796 | 0.76 | ALDH1A1 (0.32) | ALDH1A1PDF | |
| SCHEMBL7986623 | 0.76 | PSEN1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |