Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 9/20 | 0.34 |
| ▸ | MMP3 | P08254 | 6/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | MMP1 | P03956 | 4/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986624 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NPSR1 | |
| SCHEMBL7994397 | 0.79 | MMP2 (0.48) | MMP2MMP3MMP1 | |
| SCHEMBL7987308 | 0.79 | MMP2 (0.48) | MMP2MMP3MMP1 | |
| SCHEMBL7976171 | 0.77 | PDF (0.33) | ||
| SCHEMBL7989538 | 0.75 | PDF (0.43) | MMP2MMP3PDFMMP1 | |
| SCHEMBL7989540 | 0.74 | PDF (0.34) | MMP2MMP3PDFMMP1 | |
| SCHEMBL7987210 | 0.74 | PDF (0.33) | ||
| SCHEMBL7976169 | 0.73 | PDF (0.44) | MMP2MMP3PDFMMP1 | |
| SCHEMBL7977102 | 0.73 | PDF (0.44) | MMP2MMP3PDFMMP1 | |
| SCHEMBL7990024 | 0.73 | PDF (0.58) | MMP2MMP3PDFMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |