Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992337 | 0.87 | GAA (0.35) | GAATSHRSMN1; SMN2HPGDHTT | |
| SCHEMBL7975252 | 0.84 | HPGD (0.45) | GAATSHRSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7987782 | 0.84 | NPC1 (0.44) | GAATSHRSMN1; SMN2HPGDHTT | |
| SCHEMBL7987960 | 0.82 | CYP11B1 (0.32) | HPGDHTTTLR7CYP11B1CYP11B2 | |
| SCHEMBL7984378 | 0.80 | CYP11B1 (0.42) | GAASMN1; SMN2HPGDALDH1A1TLR7 | |
| SCHEMBL7974260 | 0.79 | CYP11B1 (0.47) | GAATSHRSMN1; SMN2HPGDHTT | |
| SCHEMBL7973934 | 0.78 | CYP11B1 (0.45) | GAASMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL7987442 | 0.78 | HPGD (0.46) | GAASMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL7988129 | 0.78 | MET (0.44) | GAATSHRSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985651 | 0.77 | CYP1A2 (0.41) | GAASMN1; SMN2HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |