Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARN | O95453 | 1/20 | 0.42 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992340 | 0.88 | CNOT7 (0.40) | PARNCNOT7SMN1; SMN2HPGDHTT | |
| SCHEMBL7975254 | 0.85 | CNOT7 (0.55) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7987785 | 0.85 | PARN (0.47) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7987442 | 0.84 | HPGD (0.46) | SMN1; SMN2HPGDHTTALDH1A1MEN1 | |
| SCHEMBL7987963 | 0.81 | CNOT7 (0.38) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7984380 | 0.81 | CYP11B1 (0.40) | PARNCNOT7SMN1; SMN2HPGDHTT | |
| SCHEMBL7974262 | 0.80 | ALDH1A1 (0.45) | PARNCNOT7SMN1; SMN2HPGDHTT | |
| SCHEMBL7973938 | 0.79 | CNOT7 (0.48) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985654 | 0.78 | CNOT7 (0.42) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7985346 | 0.78 | CNOT7 (0.52) | PARNCNOT7SMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |