Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447368 | 0.82 | TSHR (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL6740132 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL7670356 | 0.72 | TAAR1 (0.33) | ALDH1A1 | |
| SCHEMBL11592825 | 0.71 | CYP1A2 (0.36) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL330502 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL15547708 | 0.68 | KIF11 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9904797 | 0.67 | TSHR (0.41) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL7544397 | 0.65 | TSHR (0.63) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL24242350 | 0.65 | NOX1 (0.36) | — | |
| SCHEMBL8172805 | 0.65 | ALDH1A1 (0.39) | ALDH1A1KDM4EPKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035553-A1 | PROCESS FOR PREPARING ANDROSTENONE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-03-22 | — | — | WO | disclosed |