Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984532 | 0.92 | RAB9A (0.49) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL479876 | 0.91 | RAB9A (0.46) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL2120036 | 0.91 | RAB9A (0.46) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL3152850 | 0.89 | SMN1; SMN2 (0.49) | RAB9AKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL3152862 | 0.89 | SMN1; SMN2 (0.49) | RAB9AKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL7085728 | 0.88 | PTPN1 (0.44) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL7085734 | 0.88 | PTPN1 (0.44) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL7981209 | 0.88 | PDPK1 (0.41) | PDPK1AURKARAF1RAB9AKMT2A | |
| SCHEMBL7980713 | 0.87 | KDM4E (0.45) | PDPK1RAB9AKMT2AMEN1HIF1A | |
| SCHEMBL23252123 | 0.86 | ALDH1A1 (0.42) | PDPK1AURKARAF1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |