Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616117 | 0.88 | ALDH1A1 (0.56) | KCNH2PKMKMT2AALDH1A1TSHR | |
| SCHEMBL7412782 | 0.84 | MAPT (0.51) | KCNH2PKMKMT2AHRH3TSHR | |
| SCHEMBL7952260 | 0.84 | LTA4H (0.52) | KCNH2PKMKMT2AHRH3LTA4H | |
| SCHEMBL7642974 | 0.82 | KCNH2 (0.49) | KCNH2PKMKMT2AHRH3LTA4H | |
| SCHEMBL7551349 | 0.79 | MAPT (0.46) | KCNH2PKMKMT2AALDH1A1TSHR | |
| SCHEMBL7510431 | 0.76 | KCNH2 (0.51) | KCNH2PKMKMT2AHRH3LTA4H | |
| SCHEMBL7628372 | 0.76 | MMP1 (0.49) | — | |
| SCHEMBL7510655 | 0.75 | L3MBTL1 (0.49) | KCNH2TSHRL3MBTL1 | |
| SCHEMBL7624290 | 0.75 | LTA4H (0.49) | KCNH2PKMKMT2AHRH3LTA4H | |
| SCHEMBL7509920 | 0.75 | ALDH1A1 (0.53) | KCNH2PKMKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |