Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798811 | 0.82 | HRH3 (0.39) | HRH3HRH4 | |
| SCHEMBL4384700 | 0.81 | HRH3 (0.39) | HRH3HRH4 | |
| SCHEMBL8686305 | 0.78 | HRH3 (0.36) | HRH3HRH4 | |
| SCHEMBL4376605 | 0.78 | HRH3 (0.46) | HRH3HRH4 | |
| SCHEMBL5157531 | 0.78 | NAAA (0.35) | HRH3HRH4NAAA | |
| SCHEMBL7977532 | 0.78 | SMN1; SMN2 (0.44) | HRH3NAAA | |
| SCHEMBL7994817 | 0.77 | ACHE (0.47) | HRH3HRH4 | |
| SCHEMBL4388838 | 0.77 | HRH3 (0.38) | HRH3NAAA | |
| SCHEMBL8798359 | 0.76 | HRH3 (0.47) | HRH3HRH4 | |
| SCHEMBL480739 | 0.76 | LMNA (0.46) | HRH3HRH4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |