Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81146 | 0.86 | SMN1; SMN2 (0.37) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL80470 | 0.78 | SELL (0.36) | ALDH1A1RAPGEF4 | |
| SCHEMBL3894397 | 0.77 | RAPGEF4 (0.36) | CYP11B1CYP11B2ALDH1A1CA2POLB | |
| SCHEMBL18272234 | 0.77 | HTR2A (0.39) | CYP11B1CYP11B2ALDH1A1CA2POLB | |
| SCHEMBL83777 | 0.77 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2ALDH1A1CA2POLB | |
| SCHEMBL21892211 | 0.76 | ALDH1A1 (0.33) | CYP11B1CYP11B2ALDH1A1CA2POLB | |
| SCHEMBL26712936 | 0.74 | SMN1; SMN2 (0.41) | CYP11B1CYP11B2ALDH1A1CA2POLB | |
| SCHEMBL11067019 | 0.71 | SMN1; SMN2 (0.37) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL91657 | 0.71 | SMN1; SMN2 (0.40) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL18272233 | 0.71 | SMN1; SMN2 (0.40) | ALDH1A1CA2POLBTYRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |