Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 5/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91657 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL3894397 | 0.81 | RAPGEF4 (0.36) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL18272234 | 0.81 | HTR2A (0.39) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL17207221 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL24632461 | 0.81 | IDO1 (0.33) | CYP11B1CYP11B2RAPGEF4KIF11MPL | |
| SCHEMBL24513805 | 0.80 | CYP11B1 (0.39) | CYP11B1CYP11B2HDAC1HDAC6HTR2A | |
| SCHEMBL21139379 | 0.79 | PDE2A (0.36) | RAPGEF4KIF11MEN1KMT2A | |
| SCHEMBL21892211 | 0.79 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL13550098 | 0.78 | RAPGEF4 (0.41) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL79893 | 0.77 | CYP11B1 (0.33) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240224782-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-07-04 | — | — | US | disclosed |
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |
| WO-2023180505-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | WO | disclosed |
| US-11634445-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2022122780-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2022-06-16 | — | — | WO | disclosed |
| US-20200369699-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-26 | — | — | US | disclosed |
| US-20190315788-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-10-17 | — | — | US | disclosed |
| US-9440968-B2 | Substituted pyrido[3,2-d]pyrimidines for treating cancer | MERCK PATENT GMBH (DE) | 2016-09-13 | — | — | US | disclosed |
| US-8524721-B2 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7435455-B2 | Dihydrocoumarin derivative, liquid crystal composition containing the same, and liquid crystal display device | CHISSO CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |
| US-7435455-B2 | Dihydrocoumarin derivative, liquid crystal composition containing the same, and liquid crystal display device | CHISSO CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |
| US-20080194597-A1 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080194597-A1 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-7358257-B2 | sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives; effective for prevention and treatment of cardiovascular diseases, antithrombotic agents | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358257-B2 | sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives; effective for prevention and treatment of cardiovascular diseases, antithrombotic agents | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247355-B2 | Liquid crystal compound having chroman ring, liquid crystal composition comprising the compound and liquid crystal display device comprising the composition | CHISSO CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194597-A1 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PIGS, GP6, ASGR1 | SMN1; SMN2 3390/4885ALDH1A1 1520/4885CA2 2359/4885 |
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | SMN1; SMN2 3093/4885ALDH1A1 1379/4885CA2 2119/4885 |
| US-20200369699-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, EPCAM, SOD1 | SMN1; SMN2 2489/4885ALDH1A1 853/4885CA2 1460/4885 |
| US-20190315788-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, LEF1, ZYX | SMN1; SMN2 3901/4885ALDH1A1 656/4885CA2 2650/4885 |
| US-20240224782-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | RER1, OCIAD2, OCIAD1 | SMN1; SMN2 2441/4885ALDH1A1 617/4885CA2 3212/4885 |
| US-11634445-B2 | Organic electroluminescent materials and devices | L1CAM, EPCAM, SOD1 | SMN1; SMN2 2489/4885ALDH1A1 853/4885CA2 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.