Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 5/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83777 | 0.81 | SMN1; SMN2 (0.34) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL18272234 | 0.81 | HTR2A (0.39) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL13550091 | 0.81 | RAPGEF4 (0.40) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL21892211 | 0.79 | ALDH1A1 (0.33) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL24343525 | 0.77 | SMN1; SMN2 (0.40) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL19268220 | 0.77 | RAPGEF4 (0.41) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL79893 | 0.77 | CYP11B1 (0.33) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL26712936 | 0.77 | SMN1; SMN2 (0.41) | RAPGEF4HTR2AHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL465082 | 0.76 | KIF11 (0.34) | CYP11B1CYP11B2KIF11HSD11B1MPL | |
| SCHEMBL12621 | 0.76 | RAPGEF4 (0.52) | RAPGEF4ALDH1A1CA2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-7959990-B2 | Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light | ROLIC AG (CH) | 2011-06-14 | — | — | US | disclosed |
| US-7605134-B2 | Pesticides | MERIAL LIMITED (US) | 2009-10-20 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | ROLIC AG (CH) | 2008-11-06 | — | — | US | disclosed |
| EP-1421094-B1 | 4\"-DEOXY-4\"-(S)-AMINO AVERMECTIN DERIVATIVES | MERIAL LTD (GB) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | RAPGEF4 3540/4885HTR2A 423/4885HTR2C 830/4885 |
| US-20080274304-A1 | Functionalized Photoreactive Compounds | PCNA, PIN1, MAP1LC3C | RAPGEF4 1532/4885HTR2A 2854/4885HTR2C 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.