SCHEMBL91657

SCHEMBL91657

Cc1cc(C(F)(F)F)c(C)c(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CA2 P00918 1/20 0.40
TYR P14679 1/20 0.40
RAPGEF4 Q8WZA2 2/20 0.36
AR P10275 5/20 0.35
ACHE P22303 1/20 0.35
TSHR P16473 3/20 0.34
SYK P43405 1/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
TMPRSS4 Q9NRS4 1/20 0.34
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13550098 0.87 RAPGEF4 (0.41) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL83777 0.85 SMN1; SMN2 (0.34) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL12881255 0.83 RAPGEF4 (0.42) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL17864623 0.83 ACHE (0.56) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL15761590 0.83 SMN1; SMN2 (0.41) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL10104495 0.83 HTT (0.37) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL18272233 0.82 SMN1; SMN2 (0.40) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL3190814 0.80 CES2 (0.40) RAPGEF4MEN1KMT2A
SCHEMBL7657209 0.80 SMN1; SMN2 (0.39) SMN1; SMN2POLBALDH1A1CA2TYR
SCHEMBL24801804 0.79 MEN1 (0.37) SMN1; SMN2POLBALDH1A1CA2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395520-A2 LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2024-07-03 EP disclosed
US-20230350295-A1 CROSSLINKABLE PHOTORESIST FOR EXTREME ULTRAVIOLET LITHOGRAPHY TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-11-02 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230350295-A1 CROSSLINKABLE PHOTORESIST FOR EXTREME ULTRAVIOLET LITHOGRAPHY TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2023-11-02 US disclosed
US-20230209986-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2023-06-29 US disclosed
US-11634445-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 US disclosed
EP-3770166-B1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-10-06 EP disclosed
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-26 US disclosed
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-9868823-B2 Display device, method for manufacturing same, polyimide film for display device supporting bases, and method for producing polyimide film for display device supporting bases NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2018-01-16 US disclosed
US-20160208431-A1 FLUORINE-CONTAINING SELF-LUBRICATING FABRIC COATING MATERIAL AND METHOD FOR PREPARING THE SAME XIAMEN UNIVERSITY (CN) 2016-07-21 US disclosed
US-9312503-B2 Green light iridium (III) complex and a method of preparing the same SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2016-04-12 US disclosed
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME Shenzhen China Star Optoelectronics Technology Co. Ltd. (CN) 2015-12-10 US disclosed
US-20150183932-A1 DISPLAY DEVICE, METHOD FOR MANUFACTURING SAME, POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES, AND METHOD FOR PRODUCING POLYIMIDE FILM FOR DISPLAY DEVICE SUPPORTING BASES NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-07-02 US disclosed
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed
EP-1776438-B1 LIQUID CRYSTAL COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2008-10-08 EP disclosed
US-20080167482-A1 mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements MERCK PATENT GMBH (DE) 2008-07-10 US disclosed
US-20080167482-A1 mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements MERCK PATENT GMBH (DE) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, SOD1 SMN1; SMN2 2489/4885POLB 1236/4885ALDH1A1 853/4885
US-20150357585-A1 A GREEN LIGHT IRIDIUM (III) COMPLEX AND A METHOD OF PREPARING THE SAME ALG3, RTN3, GPR3 SMN1; SMN2 3599/4885POLB 3924/4885ALDH1A1 1491/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 SMN1; SMN2 2987/4885POLB 1899/4885ALDH1A1 1603/4885
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, ZYX SMN1; SMN2 3901/4885POLB 2189/4885ALDH1A1 656/4885
US-11634445-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, SOD1 SMN1; SMN2 2489/4885POLB 1236/4885ALDH1A1 853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.