Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974283 | 0.90 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2APNPHPGD | |
| SCHEMBL7984766 | 0.90 | HPGD (0.44) | SMN1; SMN2ALDH1A1KMT2APNPHPGD | |
| SCHEMBL7985331 | 0.89 | GRIN1 (0.45) | SMN1; SMN2ALDH1A1KMT2APKMPNP | |
| SCHEMBL7986518 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2APNPHPGD | |
| SCHEMBL7985270 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1KMT2AHPGDCNOT7 | |
| SCHEMBL7974236 | 0.87 | ABCC8 (0.43) | SMN1; SMN2ALDH1A1KMT2APNPHPGD | |
| SCHEMBL7984279 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KMT2AHPGDCYP11B2 | |
| SCHEMBL7988732 | 0.85 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AHPGDCYP11B1 | |
| SCHEMBL7988656 | 0.85 | NPY5R (0.44) | SMN1; SMN2ALDH1A1KMT2APNPHPGD | |
| SCHEMBL7985116 | 0.84 | HPGD (0.44) | SMN1; SMN2ALDH1A1KMT2APNPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |