Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974283 | 0.90 | ALDH1A1 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2APNP | |
| SCHEMBL7989418 | 0.90 | SMN1; SMN2 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2APNP | |
| SCHEMBL7988931 | 0.89 | GRIN1 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL7974236 | 0.89 | ABCC8 (0.43) | HPGDALDH1A1SMN1; SMN2KMT2APNP | |
| SCHEMBL7984716 | 0.88 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7985823 | 0.87 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7988656 | 0.85 | NPY5R (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL7984771 | 0.83 | CNOT7 (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7984419 | 0.83 | SMN1; SMN2 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL7991594 | 0.83 | HPGD (0.44) | HPGDALDH1A1SMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |