Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.45 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984771 | 0.89 | CNOT7 (0.47) | CNOT7KMT2APARNDHPSCLK1 | |
| SCHEMBL7974492 | 0.89 | ABCC8 (0.47) | CNOT7ABCC8KCNJ11KMT2APARN | |
| SCHEMBL7984934 | 0.88 | CNOT7 (0.47) | CNOT7ABCC8KCNJ11KIF11PARN | |
| SCHEMBL7974289 | 0.88 | CNOT7 (0.53) | CNOT7KMT2APARNDHPSCLK1 | |
| SCHEMBL7989422 | 0.87 | CNOT7 (0.47) | CNOT7KMT2APARNDHPSMAPT | |
| SCHEMBL7991403 | 0.84 | ABCC8 (0.43) | CNOT7ABCC8KCNJ11PARNMAPT | |
| SCHEMBL7985012 | 0.84 | ABCC8 (0.43) | CNOT7ABCC8KCNJ11PARNHDAC1 | |
| SCHEMBL7974236 | 0.84 | ABCC8 (0.43) | CNOT7ABCC8KCNJ11KIF11KMT2A | |
| SCHEMBL7988524 | 0.84 | ABCC8 (0.47) | CNOT7ABCC8KCNJ11PARNGNRHR | |
| SCHEMBL7992270 | 0.83 | ABCC8 (0.43) | CNOT7ABCC8KCNJ11PARNHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |