Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988356 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1SMN1; SMN2LMNACYP11B1 | |
| SCHEMBL7984208 | 0.88 | MAPT (0.39) | EPHX2PPARGDBHMAPTALDH1A1 | |
| SCHEMBL7987673 | 0.87 | YTHDC1 (0.47) | DBHTAAR1SMN1; SMN2YTHDC1LMNA | |
| SCHEMBL7988484 | 0.87 | PDE1A (0.43) | CDK9EPHX2PPARGDBHMAPT | |
| SCHEMBL7985513 | 0.86 | MET (0.43) | ALDH1A1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7984365 | 0.86 | HPGD (0.45) | ALDH1A1SMN1; SMN2YTHDC1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7987804 | 0.86 | YTHDC1 (0.46) | DBHTAAR1SMN1; SMN2YTHDC1LMNA | |
| Hydrochloric Acid SCHEMBL7988731 | 0.85 | MET (0.42) | ALDH1A1SMN1; SMN2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7992066 | 0.85 | HPGD (0.44) | MAPTALDH1A1SMN1; SMN2YTHDC1CYP11B1 | |
| SCHEMBL7986363 | 0.85 | GAA (0.48) | MAPTALDH1A1SMN1; SMN2YTHDC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |