Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203394 | 0.87 | NCOA1 (0.55) | L3MBTL1ALDH1A1MAPK1NCOA1NCOA3 | |
| SCHEMBL29788121 | 0.85 | NFE2L2 (0.49) | L3MBTL1ALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL357250 | 0.85 | NFE2L2 (0.49) | L3MBTL1ALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL11208196 | 0.85 | MAPK1 (0.58) | L3MBTL1ALDH1A1MAPK1HTTLTA4H | |
| Iodide SCHEMBL29162112 | 0.83 | NFE2L2 (0.47) | L3MBTL1ALDH1A1HTTKDM4ESMN1; SMN2 | |
| SCHEMBL9780765 | 0.82 | LTA4H (0.50) | L3MBTL1ALDH1A1MAPK1NCOA1NCOA3 | |
| SCHEMBL8124287 | 0.81 | STIM1 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| Methyl Alcohol SCHEMBL28815313 | 0.81 | FFAR4 (0.48) | ALDH1A1HTTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL10595717 | 0.81 | STIM1 (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNAGAA | |
| SCHEMBL11833814 | 0.80 | NCOA1 (0.51) | L3MBTL1ALDH1A1MAPK1HTTNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946495-A4 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | LILLY CO ELI (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0946495-A1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024756-A1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |