Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988767 | 0.88 | ALDH1A1 (0.35) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7992134 | 0.84 | SMN1; SMN2 (0.42) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7975413 | 0.83 | SMN1; SMN2 (0.40) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7988673 | 0.82 | TSHR (0.38) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7975316 | 0.82 | SMN1; SMN2 (0.36) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7985659 | 0.81 | RAB9A (0.45) | MASP2NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7988689 | 0.81 | ALDH1A1 (0.39) | MASP2HPGDSMN1; SMN2 | |
| SCHEMBL7993344 | 0.81 | MASP2 (0.33) | MASP2SMN1; SMN2 | |
| SCHEMBL7992455 | 0.80 | NPC1 (0.44) | NPC1HPGDRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL7974801 | 0.80 | SMN1; SMN2 (0.39) | MASP2NPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |