Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 14/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7972100 | 0.99 | CCR5 (0.41) | CCR5KCNA3USP30OPRM1OPRL1 | |
| SCHEMBL7981833 | 0.89 | HTR4 (0.47) | HTR4 | |
| Hydrochloric Acid SCHEMBL7986403 | 0.88 | HTR4 (0.47) | HTR4 | |
| SCHEMBL7989660 | 0.88 | USP30 (0.38) | USP30TPSAB1HTR4 | |
| SCHEMBL7982426 | 0.87 | LTA4H (0.47) | HTR4 | |
| SCHEMBL7989146 | 0.87 | HTR7 (0.49) | HTR4 | |
| Hydrochloric Acid SCHEMBL7985995 | 0.87 | USP30 (0.38) | USP30TPSAB1HTR4 | |
| SCHEMBL7983124 | 0.87 | HDAC3 (0.51) | HTR4 | |
| Hydrochloric Acid SCHEMBL7983742 | 0.86 | HTR7 (0.49) | HTR4 | |
| SCHEMBL7986053 | 0.86 | HTR7 (0.45) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |