Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989892 | 0.89 | RAB9A (0.35) | MEN1KMT2AATMRAB9AMAPT | |
| SCHEMBL7990339 | 0.81 | PARP1 (0.34) | MEN1KMT2AATMRAB9AMAPT | |
| SCHEMBL8002248 | 0.78 | TDP1 (0.34) | MEN1KMT2AATMRAB9AMAPT | |
| SCHEMBL7999106 | 0.74 | CCR9 (0.33) | MEN1KMT2AARALDH1A1TDP1 | |
| SCHEMBL8002841 | 0.72 | NAPRT (0.43) | MEN1KMT2ARAB9AMAPTL3MBTL1 | |
| SCHEMBL8002833 | 0.72 | P2RX7 (0.39) | MEN1KMT2ARAB9AMAPTL3MBTL1 | |
| SCHEMBL8005711 | 0.71 | PARP1 (0.32) | PARP1KCNQ3KCNQ2 | |
| SCHEMBL7999035 | 0.71 | KMT2A (0.34) | MEN1KMT2ARAB9AMAPTL3MBTL1 | |
| SCHEMBL7989856 | 0.71 | THRB (0.46) | MEN1KMT2A | |
| SCHEMBL8002360 | 0.70 | DAO (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |