Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989658 | 1.00 | ALDH1A1 (0.56) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL265578 | 0.81 | ALDH1A1 (0.69) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL10501136 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL10501143 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| Hydrochloric Acid SCHEMBL27972556 | 0.80 | ALDH1A1 (0.67) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL11815802 | 0.79 | GAA (0.56) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL10921132 | 0.79 | GAA (0.56) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL25324982 | 0.79 | CES2 (0.56) | ALDH1A1GAACYP3A4LMNATDP1 | |
| SCHEMBL9331128 | 0.79 | CES2 (0.56) | ALDH1A1GAACYP3A4LMNATDP1 | |
| SCHEMBL2784997 | 0.79 | ALDH1A1 (0.71) | ALDH1A1GAAAPPHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |