Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991764 | 0.87 | GPR84 (0.38) | GPR84ALDH1A1GSK3BADKMAPK13 | |
| SCHEMBL7991800 | 0.83 | KDM4E (0.51) | ALDH1A1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7991805 | 0.82 | KDM4E (0.48) | ALDH1A1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7989059 | 0.81 | MAPT (0.51) | ALDH1A1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7977835 | 0.81 | RAB9A (0.43) | POLBKMT2AMEN1 | |
| SCHEMBL7989339 | 0.80 | MAPK14 (0.46) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL7991880 | 0.80 | MAPK14 (0.60) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL7989973 | 0.79 | GCGR (0.43) | ALDH1A1GCGRPPARGPPARAKDM4E | |
| SCHEMBL7995032 | 0.79 | MAPK14 (0.58) | ALDH1A1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7995767 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |