SCHEMBL7989983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1497447	0.94	HDAC1 (0.35)	HDAC1HDAC3HDAC2PDCD1CD274
	SCHEMBL3225525	0.93	PDCD1 (0.38)	HDAC1HDAC6HDAC3HDAC2HDAC4
	SCHEMBL1496961	0.90	PDCD1 (0.36)	HDAC1HDAC3HDAC2PDCD1CD274
	SCHEMBL1496875	0.90	HTR5A (0.39)	HDAC1HDAC3HDAC2PDCD1CD274
	SCHEMBL1496862	0.87	HTR5A (0.40)	HDAC1HDAC3HDAC2PDCD1CD274
	SCHEMBL1496921	0.87	TRPA1 (0.34)	HDAC1PDCD1CD274ROCK1CKS1B
	SCHEMBL1497457	0.87	PDCD1 (0.37)	HDAC1PDCD1CD274ROCK1CKS1B
	SCHEMBL1496860	0.87	ROCK2 (0.38)	HDAC1HDAC3HDAC2PDCD1CD274
	SCHEMBL1496987	0.86	THRA (0.36)	HDAC1HDAC6HDAC3HDAC2PDCD1
	SCHEMBL3234544	0.86	HDAC1 (0.40)	HDAC1HDAC6HDAC3HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.