Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | NSD2 | O96028 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353840 | 1.00 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5688725 | 0.85 | VCP (0.68) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5185813 | 0.85 | ALDH1A1 (0.76) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL4903808 | 0.85 | ALDH1A1 (0.76) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5688729 | 0.85 | VCP (0.68) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27441155 | 0.83 | VCP (0.70) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7349631 | 0.82 | FDPS (0.67) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL2742571 | 0.81 | VCP (0.74) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9713042 | 0.81 | FDPS (0.68) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11232085 | 0.81 | VCP (0.74) | MAPTALDH1A1LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297257-B1 | Benzazine derivatives phosphodiesterase 4 inhibitors | ZAMBON GROUP S.P.A. (IT) | 2001-10-02 | — | — | US | disclosed |