Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57494 | 0.86 | ALDH1A1 (0.54) | MCL1ACMSDTLR8HDAC8HDAC6 | |
| SCHEMBL28336706 | 0.84 | HPRT1 (0.56) | MCL1ACMSDTLR8HDAC8HDAC6 | |
| SCHEMBL4443508 | 0.84 | PTPN22 (0.56) | PTPN22KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL14417220 | 0.83 | HSD17B1 (0.61) | MCL1ACMSDTLR8HSD17B1HSD17B2 | |
| SCHEMBL1044450 | 0.82 | HDAC4 (0.61) | ACMSDHDAC8HDAC4HDAC2HSD17B1 | |
| SCHEMBL29858254 | 0.82 | HDAC4 (0.61) | ACMSDHDAC8HDAC4HDAC2HSD17B1 | |
| SCHEMBL10028244 | 0.82 | MCL1 (0.57) | MCL1ACMSDTLR8HDAC8HDAC4 | |
| SCHEMBL31742566 | 0.82 | MCL1 (0.54) | MCL1ACMSDHDAC8HDAC4HDAC2 | |
| SCHEMBL598962 | 0.80 | GSTP1 (0.57) | MCL1ACMSDHDAC8HDAC4HDAC2 | |
| SCHEMBL30274189 | 0.80 | GSTP1 (0.57) | MCL1ACMSDHDAC8HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201123-B1 | FOR ASYMMETRIC EPOXIDATION OF ENONES; GIVES EPOXIDES HAVING AN ENHANCED OPTICAL PURITY | TECHNO POLYMER CO., LTD. (JP) | 2001-03-13 | — | — | US | claimed |
| US-6201123-B1 | FOR ASYMMETRIC EPOXIDATION OF ENONES; GIVES EPOXIDES HAVING AN ENHANCED OPTICAL PURITY | TECHNO POLYMER CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |