Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994826 | 0.92 | PDE4B (0.33) | MAPTALDH1A1TDP1FBP1GAA | |
| SCHEMBL7991148 | 0.87 | PDE4A (0.34) | FBP1PDE4AACACBACACAPDE4B | |
| SCHEMBL7996011 | 0.87 | LMNA (0.41) | ALDH1A1LMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL7908336 | 0.80 | PDE4A (0.38) | L3MBTL1FBP1PDE4APDE4BPDE4C | |
| SCHEMBL7991261 | 0.79 | HSPB1 (0.48) | RAB9AHSPB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7994691 | 0.79 | PDE4A (0.53) | PDE4A | |
| SCHEMBL7992704 | 0.78 | F7 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7991279 | 0.77 | PDE4A (0.33) | FBP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7977060 | 0.76 | HSPB1 (0.48) | RAB9AHSPB1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7904298 | 0.76 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | disclosed |