Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990957 | 0.92 | RAB9A (0.39) | PDE4BMAPTPDE4APDE4DKMT2A | |
| SCHEMBL7991148 | 0.82 | PDE4A (0.34) | PDE4BPDE4APDE4DPDE4CFBP1 | |
| SCHEMBL7996011 | 0.82 | LMNA (0.41) | PDE4BPDE4APDE4DKMT2APDE4C | |
| SCHEMBL7991156 | 0.80 | MEN1 (0.39) | PDE4BMAPTPDE4AKMT2AMEN1 | |
| SCHEMBL7908336 | 0.78 | PDE4A (0.38) | PDE4BPDE4APDE4DPDE4CFBP1 | |
| SCHEMBL7992704 | 0.76 | F7 (0.36) | PDE4BPDE4APDE4DPDE4CFFAR1 | |
| SCHEMBL7991279 | 0.75 | PDE4A (0.33) | PDE4BPDE4APDE4DPDE4CFBP1 | |
| SCHEMBL7904298 | 0.72 | PDE4A (0.43) | PDE4BPDE4APDE4DPDE4CHPGD | |
| SCHEMBL5942886 | 0.71 | MAPK1 (0.37) | PDE4BMAPTPDE4APDE4DKMT2A | |
| SCHEMBL7991261 | 0.70 | HSPB1 (0.48) | MAPTPDE4AKMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | disclosed |