Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 7/20 | 0.37 |
| ▸ | GSK3A | P49840 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996288 | 0.88 | MTNR1A (0.46) | CDC7GSK3BGSK3AROCK2ROCK1 | |
| SCHEMBL7992854 | 0.78 | GPR84 (0.41) | CDC7MAPK14MEN1KMT2AROCK2 | |
| SCHEMBL5390245 | 0.78 | PRKCA (0.43) | CDC7GSK3BMEN1KMT2AROCK2 | |
| SCHEMBL5390690 | 0.77 | GSK3B (0.48) | CDC7GSK3BMAPK14MEN1KMT2A | |
| SCHEMBL5380552 | 0.76 | XDH (0.53) | CDC7GSK3BMEN1KMT2AROCK2 | |
| SCHEMBL7993027 | 0.74 | CA1 (0.40) | CDC7GSK3BMAPK14TAAR1MEN1 | |
| SCHEMBL7978450 | 0.74 | GPR84 (0.44) | CDC7GSK3BMAPK14ROCK2GPR84 | |
| SCHEMBL7990813 | 0.74 | GPR84 (0.43) | GSK3BMEN1KMT2AGPR84 | |
| SCHEMBL7989847 | 0.73 | CDC7 (0.43) | CDC7GSK3BROCK2ROCK1 | |
| SCHEMBL7991079 | 0.72 | ALOX5 (0.41) | CDC7GSK3BMEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |