Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987851 | 0.92 | LMNA (0.46) | TP53SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7991521 | 0.91 | ADORA3 (0.47) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7988763 | 0.89 | NR1H4 (0.43) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7985375 | 0.85 | KDM4E (0.47) | TP53SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL7987920 | 0.85 | TP53 (0.47) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7985361 | 0.83 | P2RY14 (0.52) | KDM4EALDH1A1CNR1CNR2CCNA2 | |
| SCHEMBL7988637 | 0.82 | NPC1 (0.51) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7974240 | 0.82 | RAB9A (0.47) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7991586 | 0.82 | SMN1; SMN2 (0.49) | TP53SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7985249 | 0.80 | MAPT (0.48) | TP53SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |