Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.49 |
| ▸ | MMP2 | P08253 | 18/20 | 0.49 |
| ▸ | MMP1 | P03956 | 8/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005755 | 0.79 | MMP9 (0.59) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7991334 | 0.79 | MMP2 (0.40) | MMP9MMP2MMP1MMP3MMP8 | |
| SCHEMBL7998631 | 0.78 | MMP2 (0.74) | MMP9MMP2MMP1 | |
| SCHEMBL8000461 | 0.73 | MMP9 (0.54) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7365905 | 0.73 | MMP9 (0.57) | MMP9MMP2MMP1 | |
| SCHEMBL10021363 | 0.69 | MMP9 (0.74) | MMP9MMP2MMP1 | |
| SCHEMBL7998634 | 0.69 | MMP9 (0.46) | MMP9MMP2MMP1MMP13 | |
| SCHEMBL8001929 | 0.68 | MMP9 (0.71) | MMP9MMP2MMP1 | |
| SCHEMBL7539103 | 0.68 | MMP2 (0.65) | MMP9MMP2MMP1 | |
| SCHEMBL7539094 | 0.68 | MMP2 (0.65) | MMP9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294573-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPENIAS SUCH AS OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL, EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR GROWTH AND METASTASIS OR INVASION | ABBOTT LABORATORIES | 2001-09-25 | — | — | US | claimed |