Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990176 | 0.76 | DRD4 (0.45) | DRD2DRD3ADRA1B | |
| SCHEMBL7993916 | 0.69 | HTR1A (0.58) | DRD2DRD3SLC6A4 | |
| SCHEMBL3588307 | 0.68 | ALDH1A1 (0.53) | DRD2DRD3KDM4EALDH1A1SLC6A4 | |
| SCHEMBL11147698 | 0.68 | SIGMAR1 (0.63) | DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL6188172 | 0.67 | HTR1A (0.41) | DRD2DRD3SLC6A4ADRA1B | |
| SCHEMBL8671179 | 0.67 | KDM4E (0.36) | DRD2KDM4EALDH1A1SLC6A4 | |
| SCHEMBL7996612 | 0.67 | HTR1A (0.60) | DRD2DRD3KDM4EALDH1A1ADRA1B | |
| SCHEMBL7996633 | 0.65 | HTR1A (0.58) | DRD2DRD3SLC6A4 | |
| Hydrochloric Acid SCHEMBL7996501 | 0.65 | HTR1A (0.57) | DRD2DRD3SLC6A4 | |
| SCHEMBL6188196 | 0.65 | HTR1A (0.44) | DRD2SLC6A4ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| US-5136037-A | 3-(4-substituted-4-piperazinyl)butyl-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5037984-A | Anticonvulsants; anxiolytic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |