Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303832 | 0.77 | DRD4 (0.39) | DRD4HTR2AADRA1BDRD2DRD3 | |
| SCHEMBL7991398 | 0.76 | DRD2 (0.41) | ADRA1BDRD2DRD3 | |
| SCHEMBL8308708 | 0.74 | HTR2A (0.37) | DRD4HTR2ADRD2 | |
| SCHEMBL7996612 | 0.73 | HTR1A (0.60) | DRD4HTR2AADRA1BDRD2DRD3 | |
| SCHEMBL8307627 | 0.71 | HTR1A (0.37) | HTR2ADRD2 | |
| Oxalic Acid SCHEMBL7993398 | 0.69 | KDM4E (0.63) | DRD4DRD2DRD3 | |
| SCHEMBL15748300 | 0.69 | DRD2 (0.53) | DRD4DRD2DRD3 | |
| SCHEMBL10474213 | 0.68 | HTR2A (0.55) | DRD4HTR2AADRA1BDRD2 | |
| SCHEMBL8670431 | 0.67 | DRD4 (0.35) | DRD4HTR2ADRD2DRD3 | |
| SCHEMBL9759749 | 0.67 | PARP1 (0.46) | HTR2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284775-B1 | PSYCHOLOGICAL DISORDERS | AVENTIS PHARMACEUTICALS INC. | 2001-09-04 | — | — | US | disclosed |
| US-5371087-A | Antipsychotic, analgesics, anticonvulsant and anxiolytic agent | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5229388-A | 3-[4-(1-substituted-4-piperazinyl)butyl]-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-20 | — | — | US | disclosed |
| US-5136037-A | 3-(4-substituted-4-piperazinyl)butyl-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5037984-A | Anticonvulsants; anxiolytic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4933453-A | ANTIPSYCHOTIC, ANALGESIC, ANTICONVULSANT, AND ANXIOLYTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-06-12 | — | — | US | disclosed |