Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193641 | 0.83 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL7162576 | 0.83 | ADRA1D (0.54) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL7386606 | 0.78 | FAAH (0.43) | CACNA1FCACNA1DCACNA1SCACNA1CMAPT | |
| SCHEMBL6196041 | 0.78 | ALDH1A1 (0.41) | ADRA1DADRA1AADRA1BADORA3LMNA | |
| SCHEMBL6194063 | 0.76 | CACNA1F (0.41) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D | |
| SCHEMBL6196834 | 0.75 | ADRA1D (0.51) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8577372 | 0.75 | ADORA3 (0.41) | ADRA1DADRA1AADRA1BADORA3LMNA | |
| SCHEMBL7747394 | 0.75 | ADORA3 (0.41) | ADRA1DADRA1AADRA1BADORA3LMNA | |
| SCHEMBL7674379 | 0.75 | ADRA1D (0.51) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6198625 | 0.75 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BCACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228861-B1 | BENIGN PROSTATIC HYPERPLASIA; ANTICHOLESTEROL AGENTS; IMPOTENCY; INTRAOCULAR PRESSURE; ANTIARRHYTHMIA AGENTS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-08 | — | — | US | disclosed |